Improve standing reach and strength
- Trial ID
- NCT07382674
- Official Title
- Zesty Exercise System for Therapeutic Engagement
- Goal
- Improve standing reach and strength
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- Emory University
- Study Type
- INTERVENTIONAL
- Enrollment
- 46 participants
- Conditions
- Parkinson Disease
- Interventions
- ZEST-E Robot-Assisted Exercise Program
Summary For Families
The goal is to help people with mild to moderate Parkinson’s improve movement, balance, and everyday function by using targeted, repetitive exercise that promotes motor learning and strengthens neural pathways. The ZEST-E program is a robot-assisted exercise system that supports or guides limb movements, adjusts challenge levels, and gives real-time feedback so sessions are safer, more intensive, and more likely to retrain movement patterns, and it is meant to be used alongside a person’s regular medications rather than replace them. The trial is enrolling adults 40 and older with mild to moderate PD (roughly Hoehn and Yahr stages 1 to 3) who can complete study procedures and have a MoCA of 17 or higher, while excluding people with recent stroke, uncontrolled cardiac or other serious medical issues, certain psychiatric or substance use disorders, or medications that impair cognition.
Locations
- Emory University, 57 Executive Park S NE, Ste 200, Atlanta, Georgia, United States
Frequently Asked Questions
- What is this trial testing?
- This trial is studying ZEST-E Robot-Assisted Exercise Program. The goal is to help people with mild to moderate Parkinson’s improve movement, balance, and everyday function by using targeted, repetitive exercise that promotes motor learning and strengthens neural pathways. The ZEST-E program is a robot-assisted exercise system that supports or guides limb movements, adjusts challenge levels, and gives real-time feedback so sessions are safer, more intensive, and more likely to retrain movement patterns, and it is meant to be used alongside a person’s regular medications rather than replace them. The trial is enrolling adults 40 and older with mild to moderate PD (roughly Hoehn and Yahr stages 1 to 3) who can complete study procedures and have a MoCA of 17 or higher, while excluding people with recent stroke, uncontrolled cardiac or other serious medical issues, certain psychiatric or substance use disorders, or medications that impair cognition.
- Who can participate?
- Participants must be at least 40 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 1 year and 11 months.
- Will I get the real drug or a placebo?
- It depends on the trial design. Some Parkinson's trials are placebo controlled, meaning a portion of participants get an inactive comparison while others get the experimental treatment. Some use crossover designs so everyone eventually receives the active treatment at some point. Observational trials do not use a placebo at all because they are not testing a new treatment. The consent form for any specific trial spells out the design and your odds of being assigned to placebo before you enroll.
- How often will I need to visit the study site?
- Visit frequency varies by trial. Many Parkinson's studies require an in person visit every 4 to 12 weeks during the active treatment phase, with shorter or longer gaps depending on the design. The site coordinator can give you the full visit schedule before you sign anything, so you know what the time commitment looks like.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Will travel or parking be reimbursed?
- Many trials reimburse for parking, mileage, and sometimes lodging if the site is far from your home. Reimbursement policies vary by sponsor and site. When you contact the trial team, ask specifically what is covered and how reimbursement is processed.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.