Detect Parkinson and track severity
- Trial ID
- NCT07392411
- Official Title
- Study on Artificial Intelligence-Based Facial and Speech-Related Patterns in Parkinson's Disease and Their Digital Biomarkers
- Goal
- Detect Parkinson and track severity
- Status
- RECRUITING
- Sponsor
- Beijing Tiantan Hospital
- Study Type
- OBSERVATIONAL
- Enrollment
- 720 participants
- Conditions
- Parkinson's Disease, Progressive Supranuclear Palsy(PSP), Multiple System Atrophy, Healthy Control
- Interventions
- video recording
Summary For Families
Researchers are using AI to detect and quantify subtle changes in facial expression and speech that could become digital biomarkers to help detect Parkinson's disease, distinguish Parkinson-plus conditions like PSP and MSA, and track disease severity over time. They record short videos and audio of your face and voice, then use algorithms to measure things like reduced facial expressivity, slowed or softer speech, altered pitch and timing, and other motor-related voice signals, all noninvasively and without changing your medications. The study is looking for adults 18 to 75 with diagnosed PD, PSP, or MSA, plus healthy controls who can consent and tolerate recording; people with significant cognitive impairment (MMSE ≤ 24), major brain injury or surgery, severe dyskinesia that prevents reliable recording, and other listed exclusions are not eligible.
Locations
- 首都医科大学附属北京天坛医院, Beijing, Beijing Municipality, China
Frequently Asked Questions
- What is this trial testing?
- This trial is studying video recording. Researchers are using AI to detect and quantify subtle changes in facial expression and speech that could become digital biomarkers to help detect Parkinson's disease, distinguish Parkinson-plus conditions like PSP and MSA, and track disease severity over time. They record short videos and audio of your face and voice, then use algorithms to measure things like reduced facial expressivity, slowed or softer speech, altered pitch and timing, and other motor-related voice signals, all noninvasively and without changing your medications. The study is looking for adults 18 to 75 with diagnosed PD, PSP, or MSA, plus healthy controls who can consent and tolerate recording; people with significant cognitive impairment (MMSE ≤ 24), major brain injury or surgery, severe dyskinesia that prevents reliable recording, and other listed exclusions are not eligible.
- Who can participate?
- Participants must be between 15 Years and 75 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 3 years and 5 months.
- Will I get the real drug or a placebo?
- It depends on the trial design. Some Parkinson's trials are placebo controlled, meaning a portion of participants get an inactive comparison while others get the experimental treatment. Some use crossover designs so everyone eventually receives the active treatment at some point. Observational trials do not use a placebo at all because they are not testing a new treatment. The consent form for any specific trial spells out the design and your odds of being assigned to placebo before you enroll.
- How often will I need to visit the study site?
- Visit frequency varies by trial. Many Parkinson's studies require an in person visit every 4 to 12 weeks during the active treatment phase, with shorter or longer gaps depending on the design. The site coordinator can give you the full visit schedule before you sign anything, so you know what the time commitment looks like.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Will travel or parking be reimbursed?
- Many trials reimburse for parking, mileage, and sometimes lodging if the site is far from your home. Reimbursement policies vary by sponsor and site. When you contact the trial team, ask specifically what is covered and how reimbursement is processed.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.