Improve gait with C Mill
- Trial ID
- NCT07434089
- Official Title
- Gut-Brain Axis and Rehabilitation: Study on the Effects of C-Mill Technology on the Intestinal Microbiota of Parkinson's Disease Patients
- Goal
- Improve gait with C Mill
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
- Study Type
- INTERVENTIONAL
- Enrollment
- 60 participants
- Conditions
- Parkinson Disease
- Interventions
- C-Mill technology treadmill equipped with semi-immersive VR, C-Mill treatment without semi-immersive virtual reality (VR), Conventional physiotherapy training
Plain-Language Summary
Researchers are testing whether targeted gait rehabilitation using the C-Mill can shift the intestinal microbiota via the gut-brain axis, which might relate to motor and non-motor Parkinson's symptoms. The C-Mill is an instrumented treadmill that delivers precise walking tasks, real-time feedback and semi-immersive virtual reality scenes to challenge and retrain gait and balance, the trial compares C-Mill with VR, C-Mill without VR, and conventional physiotherapy to see if that sensorimotor stimulation changes gut signals and bacterial communities. The study is enrolling about 60 people aged 40 to 70 with moderate to advanced PD, Hoehn and Yahr stages 2 to 4, who can walk independently. People with major gastrointestinal disease, recent antibiotics/probiotics or drugs that affect GI motility, recent GI surgery, or extreme height/weight are excluded.
Locations
- Irccs Centro Neurolesi Bonino Pulejo, Messina, Messina, Italy
Frequently Asked Questions
- What is this trial testing?
- This trial is studying C-Mill technology treadmill equipped with semi-immersive VR. Researchers are testing whether targeted gait rehabilitation using the C-Mill can shift the intestinal microbiota via the gut-brain axis, which might relate to motor and non-motor Parkinson's symptoms. The C-Mill is an instrumented treadmill that delivers precise walking tasks, real-time feedback and semi-immersive virtual reality scenes to challenge and retrain gait and balance, the trial compares C-Mill with VR, C-Mill without VR, and conventional physiotherapy to see if that sensorimotor stimulation changes gut signals and bacterial communities. The study is enrolling about 60 people aged 40 to 70 with moderate to advanced PD, Hoehn and Yahr stages 2 to 4, who can walk independently. People with major gastrointestinal disease, recent antibiotics/probiotics or drugs that affect GI motility, recent GI surgery, or extreme height/weight are excluded.
- Who can participate?
- Participants must be between 40 Years and 70 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 2 years.