NEUROTECHNO (NCT07467460)
Early blood tests detect Parkinson
- Trial ID
- NCT07467460
- Official Title
- NEUROTECHNO: Precision Medicine and Neurodegenerative Diseases: Advanced Systems for the Diagnosis and Treatment of Parkinson's Disease and Alzheimer's Disease.
- Study Acronym
- NEUROTECHNO
- Goal
- Early blood tests detect Parkinson
- Status
- RECRUITING
- Sponsor
- Neuromed IRCCS
- Study Type
- OBSERVATIONAL
- Enrollment
- 500 participants
- Conditions
- PARKINSON DISEASE (Disorder), Alzheimer s Disease, Diabete Type 2
Summary For Families
The goal is to create new, minimally invasive ways to predict and monitor early Parkinson's and Alzheimer's, and to better understand how type 2 diabetes may raise the risk or change how these diseases progress. The project will observe people across several centers and study existing and new blood, DNA and cell samples, brain scans, and tests of metabolism and gene activity, then combine those results to find biological markers and altered pathways linked to disease. Those discoveries will be used to design and test prototype early‑diagnosis kits and a personalized system for tracking patients over time within the health system. Adults 18 and older can join: Parkinson's participants must have at least two main signs (one must be tremor or slowed movement), no early atypical features, and a recorded response to levodopa or similar drugs or no adequate trial; Alzheimer's participants need a probable Alzheimer's diagnosis supported by an amyloid brain scan or spinal fluid test, and people with major psychiatric disorders or other neurodegenerative diseases are excluded.
Locations
- IRCCS INM Neuromed, Pozzilli, Italy
Frequently Asked Questions
- What is this trial testing?
- This trial is studying an experimental treatment. The goal is to create new, minimally invasive ways to predict and monitor early Parkinson's and Alzheimer's, and to better understand how type 2 diabetes may raise the risk or change how these diseases progress. The project will observe people across several centers and study existing and new blood, DNA and cell samples, brain scans, and tests of metabolism and gene activity, then combine those results to find biological markers and altered pathways linked to disease. Those discoveries will be used to design and test prototype early‑diagnosis kits and a personalized system for tracking patients over time within the health system. Adults 18 and older can join: Parkinson's participants must have at least two main signs (one must be tremor or slowed movement), no early atypical features, and a recorded response to levodopa or similar drugs or no adequate trial; Alzheimer's participants need a probable Alzheimer's diagnosis supported by an amyloid brain scan or spinal fluid test, and people with major psychiatric disorders or other neurodegenerative diseases are excluded.
- Who can participate?
- Participants must be at least 18 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 2 years and 7 months.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- This is an observational study, so there is no placebo and no experimental treatment is assigned. Researchers observe and collect information while you continue your usual care.
- What procedures are involved in this trial?
- Based on the protocol, this trial involves: MRI scan (non-invasive). Confirm the full schedule with the study coordinator.