Parkinson's Trial NCT07485621
Guide brain stimulation contact selection
- Trial ID
- NCT07485621
- Official Title
- Assessing the Relation Between Subcortical LFPs and DBS Parameter Selection in Parkinson's Disease - a Prospective Study
- Goal
- Guide brain stimulation contact selection
- Status
- RECRUITING
- Sponsor
- Loes Laurijssen
- Study Type
- OBSERVATIONAL
- Enrollment
- 40 participants
- Conditions
- Parkinson's Disease (PD)
Summary For Families
Goal: To find out whether choosing which electrode contact to use on a deep brain stimulation device can be guided by recordings of electrical activity from deep brain areas, called local field potentials, and whether those recording-based choices match the contacts clinicians pick after routine testing. Approach: Participants will have these brain recordings taken as part of their regular hospital visits, and researchers will compare the contact choices suggested by the recordings with the clinically optimized contact selection. Eligibility: Adults 18 and older with a standard clinical diagnosis of Parkinson's disease who have been approved for deep brain stimulation to treat movement symptoms that have not responded well to other treatments, and who can understand Dutch or French.
Locations
- University Hospitals Leuven, Leuven, Vlaams-Brabant, Belgium
Frequently Asked Questions
- What is this trial testing?
- This trial is studying an experimental treatment. Goal: To find out whether choosing which electrode contact to use on a deep brain stimulation device can be guided by recordings of electrical activity from deep brain areas, called local field potentials, and whether those recording-based choices match the contacts clinicians pick after routine testing. Approach: Participants will have these brain recordings taken as part of their regular hospital visits, and researchers will compare the contact choices suggested by the recordings with the clinically optimized contact selection. Eligibility: Adults 18 and older with a standard clinical diagnosis of Parkinson's disease who have been approved for deep brain stimulation to treat movement symptoms that have not responded well to other treatments, and who can understand Dutch or French.
- Who can participate?
- Participants must be at least 18 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 3 years.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- This is an observational study, so there is no placebo and no experimental treatment is assigned. Researchers observe and collect information while you continue your usual care.
- What procedures are involved in this trial?
- Based on the protocol, this trial involves: Brain surgery / implanted device (invasive). Confirm the full schedule with the study coordinator.