Repetitive Transcranial Magnetic S… for Parkinson's (NCT07488026)
Reduce freezing episodes while walking
- Trial ID
- NCT07488026
- Official Title
- Effects of the Stimulation Site of Trans-spinal Magnetic Stimulation Combined With Transcranial Magnetic Stimulation on Functional Mobility in Individuals With Parkinson's Disease
- Goal
- Reduce freezing episodes while walking
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- Universidade Federal de Pernambuco
- Study Type
- INTERVENTIONAL
- Enrollment
- 30 participants
- Conditions
- Parkinson's Disease (PD), Gait Disorders, Transcranial Magnetic Stimulation, Spinal Cord Stimulation
- Interventions
- Repetitive Transcranial Magnetic Stimulation, Cervical Trans-spinal Magnetic Stimulation, Thoracic Trans-spinal Magnetic Stimulation
Summary For Families
Researchers are testing whether pairing magnetic pulses to the brain with magnetic pulses to the spine can improve walking and other mobility problems in Parkinson's, and whether placing the spinal pulses at the neck or the upper back works better. Participants will receive ten sessions that combine repetitive transcranial magnetic stimulation, which delivers magnetic pulses to the brain, with trans-spinal magnetic stimulation applied either to the cervical (neck) or thoracic (upper back) spine, and the team will track walking speed, freezing of gait (when the feet feel stuck), overall movement, balance, quality of life, and any side effects. Adults 40 and older with a neurologist-confirmed Parkinson's diagnosis, stable dopamine-related medication for at least three months, moderate disease stage (2.5 to 3 on the modified Hoehn and Yahr scale), and at least one freezing episode per week can join; people with other certain neurological or medical problems, low cognitive scores, prior Parkinson's surgery, a history of seizures, or metal implants in the neck or spine are excluded.
Locations
- Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Repetitive Transcranial Magnetic Stimulation. Researchers are testing whether pairing magnetic pulses to the brain with magnetic pulses to the spine can improve walking and other mobility problems in Parkinson's, and whether placing the spinal pulses at the neck or the upper back works better. Participants will receive ten sessions that combine repetitive transcranial magnetic stimulation, which delivers magnetic pulses to the brain, with trans-spinal magnetic stimulation applied either to the cervical (neck) or thoracic (upper back) spine, and the team will track walking speed, freezing of gait (when the feet feel stuck), overall movement, balance, quality of life, and any side effects. Adults 40 and older with a neurologist-confirmed Parkinson's diagnosis, stable dopamine-related medication for at least three months, moderate disease stage (2.5 to 3 on the modified Hoehn and Yahr scale), and at least one freezing episode per week can join; people with other certain neurological or medical problems, low cognitive scores, prior Parkinson's surgery, a history of seizures, or metal implants in the neck or spine are excluded.
- Who can participate?
- Participants must be at least 40 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 10 months.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- There is no placebo group. Everyone receives an active treatment; the study compares one treatment against another.
- How many visits does this trial involve?
- You will undergo 10 treatment sessions.