Improve movement with brain stimulation
- Trial ID
- NCT07524400
- Official Title
- Effects of the Combination of Physical Exercise and Transcranial Direct Current Stimulation on Motor Function and Underlying Neurophysiological Mechanisms in Parkinson's Disease
- Goal
- Improve movement with brain stimulation
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- Universidad Rey Juan Carlos
- Study Type
- INTERVENTIONAL
- Enrollment
- 100 participants
- Conditions
- Parkinson' Disease
- Interventions
- real tDCS and exercise, Sham tDCS and exercise, Exercise
Plain-Language Summary
The trial asks whether pairing exercise with noninvasive brain stimulation can improve motor function and the underlying brain activity that supports movement in Parkinson's. Participants do supervised exercise while receiving either real transcranial direct current stimulation, sham stimulation, or exercise alone; tDCS delivers a low electrical current across the scalp to boost cortical excitability and plasticity, which may enhance motor learning and rehabilitation, and it is given alongside stable antiparkinsonian medications rather than replacing levodopa. About 100 adults with idiopathic Parkinson's diagnosed by UK Brain Bank criteria and on stable meds are sought, while people with significant cognitive impairment, major depression, seizure history, deep brain stimulators or other implanted electronic devices, severe heart disease, recent stroke or major orthopedic problems are excluded.
Locations
- Center of Sport Research, Fuenlabrada, Madrid, Spain
Frequently Asked Questions
- What is this trial testing?
- This trial is studying real tDCS and exercise. The trial asks whether pairing exercise with noninvasive brain stimulation can improve motor function and the underlying brain activity that supports movement in Parkinson's. Participants do supervised exercise while receiving either real transcranial direct current stimulation, sham stimulation, or exercise alone; tDCS delivers a low electrical current across the scalp to boost cortical excitability and plasticity, which may enhance motor learning and rehabilitation, and it is given alongside stable antiparkinsonian medications rather than replacing levodopa. About 100 adults with idiopathic Parkinson's diagnosed by UK Brain Bank criteria and on stable meds are sought, while people with significant cognitive impairment, major depression, seizure history, deep brain stimulators or other implanted electronic devices, severe heart disease, recent stroke or major orthopedic problems are excluded.
- Who can participate?
- Eligibility criteria vary. Check the full listing on ClinicalTrials.gov for detailed inclusion and exclusion criteria.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 3 months.