Parkinson's Trial NCT07585409

Identify why physical activity declines

Trial ID
NCT07585409
Official Title
Physical Activity in Persons With Parkinson's Disease - a Longitudinal Cohort Study
Goal
Identify why physical activity declines
Status
RECRUITING
Sponsor
Karolinska Institutet
Study Type
OBSERVATIONAL
Enrollment
450 participants
Conditions
PARKINSON DISEASE (Disorder), Physical Activity, Sedentary Behaviors

Summary For Families

The goal is to understand how physical activity and sedentary behavior relate to symptoms and progression in people with Parkinson's, so clinicians can better tailor activity advice and spot early signs of decline. The approach is observational, following a cohort over time with repeated physical activity and clinical assessments to map movement patterns and symptom changes rather than testing a drug or device. They are looking for adults 18 and older with idiopathic Parkinson's at Hoehn and Yahr stages 1 to 4, excluding those who are wheelchair bound or bedridden (H&Y 5) or unable to complete the critical activity and clinical tests. The study plans to enroll about 450 people and starts in January 2026.

Locations

  • Karolinska University Hospital, Stockholm, Sweden

Frequently Asked Questions

What is this trial testing?
This trial is studying an experimental treatment. The goal is to understand how physical activity and sedentary behavior relate to symptoms and progression in people with Parkinson's, so clinicians can better tailor activity advice and spot early signs of decline. The approach is observational, following a cohort over time with repeated physical activity and clinical assessments to map movement patterns and symptom changes rather than testing a drug or device. They are looking for adults 18 and older with idiopathic Parkinson's at Hoehn and Yahr stages 1 to 4, excluding those who are wheelchair bound or bedridden (H&Y 5) or unable to complete the critical activity and clinical tests. The study plans to enroll about 450 people and starts in January 2026.
Who can participate?
Participants must be at least 18 Years.
Where is this trial located?
This trial is recruiting at 1 location.
Does it cost anything to join?
No. There is no cost to participate. Study-related care and treatment are provided at no charge.
How long does the trial last?
This trial is estimated to last approximately 4 years and 11 months.
Can I leave the trial if I change my mind?
Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
Can my spouse or care partner come with me to visits?
In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
Will I get a placebo in this trial?
This is an observational study, so there is no placebo and no experimental treatment is assigned. Researchers observe and collect information while you continue your usual care.
What procedures are involved in this trial?
Based on the protocol, this trial involves: Questionnaires & surveys (non-invasive); Wearable / at-home monitoring (non-invasive). Confirm the full schedule with the study coordinator.

Related Reading

View on ClinicalTrials.gov