Parkinson's Trial NCT07585409
Identify why physical activity declines
- Trial ID
- NCT07585409
- Official Title
- Physical Activity in Persons With Parkinson's Disease - a Longitudinal Cohort Study
- Goal
- Identify why physical activity declines
- Status
- RECRUITING
- Sponsor
- Karolinska Institutet
- Study Type
- OBSERVATIONAL
- Enrollment
- 450 participants
- Conditions
- PARKINSON DISEASE (Disorder), Physical Activity, Sedentary Behaviors
- Registry Record Last Updated
- 2026-05-15 (2 months ago)
- Estimated Commitment
- Lower commitment estimated from the protocol. This reflects time and procedures only — confirm details with the study coordinator.
Summary For Families
The goal is to understand how physical activity and sedentary behavior relate to symptoms and progression in people with Parkinson's, so clinicians can better tailor activity advice and spot early signs of decline. The approach is observational, following a cohort over time with repeated physical activity and clinical assessments to map movement patterns and symptom changes rather than testing a drug or device. They are looking for adults 18 and older with idiopathic Parkinson's at Hoehn and Yahr stages 1 to 4, excluding those who are wheelchair bound or bedridden (H&Y 5) or unable to complete the critical activity and clinical tests. The study plans to enroll about 450 people and starts in January 2026.
Locations
- Karolinska University Hospital, Stockholm, Sweden
Making Contact: How to Call This Study Site
Who to ask for
Ask for the study coordinator. Some sites call this person the research coordinator. They are the right person for questions about joining a study. If you reach a front desk or a doctor's office scheduler, ask them to connect you with the research team for this study.
What to say
It is fine to read this out loud, word for word:
Hello, my name is ____. I am calling about a Parkinson's study at your site. The study number is NCT07585409. It is the one about "Identify why physical activity declines". Could I speak with the study coordinator about taking part?
If you are calling for a family member, use their name and mention that you help with their care.
What they will ask you
- The year of diagnosis
- Current medications and their doses
- Other health conditions
- Any procedures already done, such as deep brain stimulation (DBS)
- How far you are able to travel for study visits
- Whether a care partner can come to visits with you
What to have ready
- A written list of current medications and doses
- Your neurologist's name and phone number
- The diagnosis date. The year is enough.
- A recent visit summary from the neurologist, if you have one
What to ask them
- How many visits are there, and how long does each visit take?
- Is travel, parking, or my time reimbursed?
- Is there a placebo group, and what is my chance of being in it? The listing already answers this: This is an observational study, so there is no placebo and no experimental treatment is assigned. Researchers observe and collect information while you continue your usual care. Ask the coordinator to confirm it still applies.
- Would I need to stop or pause any of my current medications?
- What happens when the study ends? Could I stay on the treatment if it helps?
What to expect
- Expect to wait a few days for a callback. A week is common. Calling or emailing again after that is fine and normal.
- Many callers do not end up joining. Screening out is common and is not a judgment about you or your health.
- Asking questions commits you to nothing. You can stop the process at any point.
Frequently Asked Questions
- What is this trial testing?
- This trial is studying an experimental treatment. The goal is to understand how physical activity and sedentary behavior relate to symptoms and progression in people with Parkinson's, so clinicians can better tailor activity advice and spot early signs of decline. The approach is observational, following a cohort over time with repeated physical activity and clinical assessments to map movement patterns and symptom changes rather than testing a drug or device. They are looking for adults 18 and older with idiopathic Parkinson's at Hoehn and Yahr stages 1 to 4, excluding those who are wheelchair bound or bedridden (H&Y 5) or unable to complete the critical activity and clinical tests. The study plans to enroll about 450 people and starts in January 2026.
- Who can participate?
- Participants must be at least 18 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- Being asked to pay to join a trial is a red flag: legitimate trials do not charge a participation fee, and the study treatment and study-specific tests are provided by the trial sponsor. What you might still pay depends on where you live: in the US, routine care you would receive anyway can be billed to you or your insurance; trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- This trial is estimated to last approximately 4 years and 11 months.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- This is an observational study, so there is no placebo and no experimental treatment is assigned. Researchers observe and collect information while you continue your usual care.
- What procedures are involved in this trial?
- Based on the protocol, this trial involves: Questionnaires & surveys (non-invasive); Wearable / at-home monitoring (non-invasive). Confirm the full schedule with the study coordinator.