Quadriceps Neuromuscular Electrica… for Parkinson's (NCT07589296)
Improve walking speed and balance
- Trial ID
- NCT07589296
- Official Title
- Comparative Effects of Robot-Assisted Gait Training and Quadriceps Neuromuscular Electrical Stimulation Added to Standard Exercise Rehabilitation on Balance, Gait, Disease Severity, and Quadriceps Muscle Adaptations in Patients With Parkinson Disease: A Prospective Randomized Assessor-Blinded Clinical Trial
- Goal
- Improve walking speed and balance
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
- Study Type
- INTERVENTIONAL
- Enrollment
- 40 participants
- Conditions
- Parkinson Disease (PD)
- Interventions
- Quadriceps Neuromuscular Electrical Stimulation (NMES), robot -assisted gait training
Summary For Families
Researchers are comparing whether adding robot-assisted gait training or electrical stimulation of the quadriceps to standard exercise rehab does a better job of improving balance, walking, overall Parkinson's severity, and changes in thigh muscle. The robot guides and supports repeated, task-specific walking to retrain gait and balance, while neuromuscular electrical stimulation sends small pulses to make the quadriceps contract, strengthening the muscle and improving activation; both are delivered on top of usual rehab exercises. The trial is looking for people aged 40 to 80 with mild to moderate Parkinson's (Hoehn and Yahr stage II,III) who can walk independently, are on stable medications, can follow instructions, and do not have severe cognitive, cardiovascular, or musculoskeletal problems or implanted electronic devices like pacemakers.
Locations
- Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey, Küçükçekmece, Istanbul, Turkey (Türkiye)
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Quadriceps Neuromuscular Electrical Stimulation (NMES). Researchers are comparing whether adding robot-assisted gait training or electrical stimulation of the quadriceps to standard exercise rehab does a better job of improving balance, walking, overall Parkinson's severity, and changes in thigh muscle. The robot guides and supports repeated, task-specific walking to retrain gait and balance, while neuromuscular electrical stimulation sends small pulses to make the quadriceps contract, strengthening the muscle and improving activation; both are delivered on top of usual rehab exercises. The trial is looking for people aged 40 to 80 with mild to moderate Parkinson's (Hoehn and Yahr stage II,III) who can walk independently, are on stable medications, can follow instructions, and do not have severe cognitive, cardiovascular, or musculoskeletal problems or implanted electronic devices like pacemakers.
- Who can participate?
- Participants must be between 40 Years and 80 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- The estimated duration for this trial is not yet available. Trials typically last several months to a few years depending on the study design.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- There is no placebo group. Everyone receives an active treatment; the study compares one treatment against another.
- How many visits does this trial involve?
- You will be evaluated at baseline, at the end of the six-week treatment period, and at follow-up in week 14.
- What procedures are involved in this trial?
- Based on the protocol, this trial involves: Ultrasound (non-invasive). Confirm the full schedule with the study coordinator.