Stem-Cell and Cell Therapy Clinical Trials for Parkinson's
Stem-cell therapy is one of the most talked-about frontiers in Parkinson's research. The idea is to replace the dopamine-producing brain cells lost to the disease using new cells grown from stem cells, rather than only compensating for the dopamine that is missing.
These are early-stage, surgical studies focused first on safety and on whether the transplanted cells survive and work. They are a fundamentally different approach from a pill, and the field is moving quickly.
Below are the recruiting trials we track that involve stem-cell or cell-replacement therapy. Sign up to be emailed when a new one opens.
20 Recruiting Stem-Cell Therapy Trials
- Improve walking and reduce stiffness, NCT07572071, PHASE1, RECRUITING
- Identify genetic causes of Parkinson, NCT05721911, RECRUITING
- Cell transplant improves motor symptoms, NCT07102342, PHASE1, PHASE2, RECRUITING
- Cell implant reduces off time, NCT06687837, PHASE1, RECRUITING
- Restore dopamine to improve movement, NCT06753331, PHASE1, PHASE2, RECRUITING
- Restore dopamine to improve walking, NCT05901818, PHASE1, RECRUITING
- Brain injection reduces movement problems, NCT07195825, PHASE1, RECRUITING
- Replace lost dopamine producing neurons, NCT06608355, PHASE1, RECRUITING
- Reduce medication wearing off symptoms, NCT06145711, RECRUITING
- Replace lost dopamine producing neurons, NCT06167681, PHASE1, PHASE2, RECRUITING
- Donor cell injections reduce tremor, NCT06978920, PHASE1, RECRUITING
- Restore dopamine production in putamen, NCT07106021, PHASE1, PHASE2, RECRUITING
- Gene therapy improves motor control, NCT07100171, EARLY_PHASE1, RECRUITING
- Assess intranasal AlloEx exosome safety, NCT05152394, PHASE1, RECRUITING
- Cell transplant reduces off time, NCT07080775, PHASE1, RECRUITING
- Enable new Parkinson treatment development, NCT06203106, RECRUITING
- Reduce daily off medication time, NCT06944522, PHASE3, RECRUITING
- Reduce off period motor fluctuations, NCT07166757, PHASE1, PHASE2, RECRUITING
- Transplant restores dopamine producing cells, NCT06482268, PHASE1, RECRUITING
- Create personalized stem cell therapies, NCT00874783, RECRUITING