Clinical Trials for Newly Diagnosed Parkinson's
Being newly diagnosed with Parkinson's is overwhelming, but it is also the stage when the most clinical trials are open to you. Many disease-modifying studies — the ones testing whether a treatment can slow Parkinson's down — specifically look for people in the first few years after diagnosis, before symptoms have advanced.
These trials often use phrases like "early-stage", "de novo", "newly diagnosed", or "within 2 years of diagnosis" in who they can enroll. Some also look for people who have not yet started medication, which we track on a separate page.
Below are the recruiting trials we track that are open to people in the early stages of Parkinson's. Sign up to be emailed when a new one opens.
56 Recruiting Newly Diagnosed Trials
- Probiotic cocktail delays Parkinson progression, NCT07619560, RECRUITING
- Determine if sleep affects thinking, NCT07536490, RECRUITING
- Multitasking exercises improve arm strength, NCT07536542, RECRUITING
- Exoskeleton improves balance while walking, NCT07567482, RECRUITING
- Reduce tremor and movement stiffness, NCT07572903, RECRUITING
- Improve walking endurance through exercise, NCT07221266, RECRUITING
- Improve movement and speech function, NCT07568067, RECRUITING
- Find tests predicting Parkinson progression, NCT07533799, RECRUITING
- Home brain stimulation improves walking, NCT07518290, RECRUITING
- New medication improves brain energy, NCT07322887, PHASE2, RECRUITING
- Improve balance through mental rehearsal, NCT07495462, RECRUITING
- Lemborexant improves motor and sleep, NCT07384429, PHASE4, RECRUITING
- Reduce freezing episodes while walking, NCT07488026, RECRUITING
- Improve hand dexterity with phygital, NCT07475741, RECRUITING
- Wearable cues reduce daily freezing, NCT06416345, RECRUITING
- Slow Parkinson progression through lifestyle, NCT07443293, PHASE2, RECRUITING
- Improve walking with robotic treadmill, NCT04087031, RECRUITING
- Improve cognition via resistance training, NCT04796506, RECRUITING
- Brain injection clears sticky protein, NCT07157345, PHASE1, RECRUITING
- New medication slows early progression, NCT07174310, PHASE3, RECRUITING
- Gentle ear stimulation improves movement, NCT06409338, RECRUITING
- Improve balance using telerehabilitation games, NCT05773885, RECRUITING
- Detect subtle walking changes early, NCT06907589, RECRUITING
- Improve arm dexterity with robotics, NCT06906679, RECRUITING
- Improve vision guided reaching ability, NCT05400499, RECRUITING
- Restore glucocerebrosidase activity in putamen, NCT05565443, RECRUITING
- Track early Parkinson disease progression, NCT05767151, RECRUITING
- Reduce toxic brain protein clumps, NCT06565195, PHASE1, RECRUITING
- Slow early Parkinson disease progression, NCT06680830, PHASE2, RECRUITING
- Improve posture and trunk flexibility, NCT06536478, RECRUITING
- Reduce lower extremity muscle stiffness, NCT05884944, RECRUITING
- Detect early Parkinson via blood, NCT05385315, RECRUITING
- Improve motor symptoms via glucose, NCT05998772, RECRUITING
- Predict falls by mapping movements, NCT06405334, RECRUITING
- Increase walking speed and endurance, NCT06707402, RECRUITING
- Test radotinib to slow progression, NCT04691661, PHASE2, RECRUITING
- Map Parkinson brain immune activity, NCT05205291, RECRUITING
- Improve everyday movement and thinking, NCT06879821, RECRUITING
- Reduce falls by improving balance, NCT06508801, RECRUITING
- Reduce tremor slowness and stiffness, NCT04681534, RECRUITING
- Silymarin slows Parkinson disease progression, NCT07001150, PHASE2, RECRUITING
- Improve walking reduce caregiver burden, NCT06892717, RECRUITING
- Improve gait and balance remotely, NCT06052280, RECRUITING
- Improve balance with motor imagery, NCT06154356, RECRUITING
- Detect Parkinson using gut biopsy, NCT05347407, RECRUITING
- Retinal imaging detects early Parkinson, NCT07244640, RECRUITING
- Identify motor plasticity affecting walking, NCT05286736, RECRUITING
- Detect early Parkinsons via oculography, NCT04731246, RECRUITING
- Brain scan detects immune activity, NCT05395624, PHASE1, PHASE2, RECRUITING
- Reduce slowness stiffness and tremor, NCT05268887, RECRUITING