Clinical Trials for People Not Yet on Parkinson's Medication
Some Parkinson's trials specifically enroll people who have not yet started medication, often called "levodopa-naïve", "treatment-naïve", or "untreated". Researchers look for this group because it lets them measure a new treatment's effect without the influence of existing Parkinson's drugs.
If you have recently been diagnosed and are still deciding when to begin treatment, these studies may be especially relevant. Taking part does not usually mean going without care. Many trials still allow you to start standard medication if and when you need it.
Below are the recruiting trials we track that are open to people not yet on Parkinson's medication. Sign up to be emailed when a new one opens.
32 Recruiting Not Yet on Medication Trials
- Improve eye alignment and refocusing, NCT06857851, RECRUITING
- Reduce under and over stimulation, NCT07682311, RECRUITING
- New medication slows Parkinson progression, NCT07666022, PHASE1, RECRUITING
- Brain stimulation improves sleep quality, NCT07636720, RECRUITING
- Reduce tremor using sound waves, NCT07207122, RECRUITING
- Personalize brain stimulation for movement, NCT07398157, RECRUITING
- New medication improves brain energy, NCT07322887, PHASE2, RECRUITING
- Document motor complications despite medication, NCT07330258, RECRUITING
- Transplant cells to improve movement, NCT07102342, PHASE1, PHASE2, RECRUITING
- Image brain cyclooxygenase related inflammation, NCT04396873, PHASE1, RECRUITING
- Reduce nighttime awakenings with stimulation, NCT05070013, RECRUITING
- Test biophoton therapy for tremor, NCT06147999, RECRUITING
- Brain stimulation improves eye alignment, NCT05400499, RECRUITING
- Track early Parkinson disease progression, NCT05767151, RECRUITING
- Determine whether immunosuppression slows progression, NCT06834191, RECRUITING
- Neck drainage surgery slows progression, NCT06852352, RECRUITING
- Assess safety of Parkinson medication, NCT06809400, PHASE1, RECRUITING
- Nighttime brain stimulation improves sleep, NCT07110376, RECRUITING
- Assess experimental pain in Parkinsons, NCT05981261, RECRUITING
- Improve walking speed with exercise, NCT06088355, RECRUITING
- Measure brain inflammation in Parkinson, NCT05205291, RECRUITING
- Safety of new Parkinson medication, NCT07284784, PHASE2, PHASE3, RECRUITING
- Measure emotional response to music, NCT06688968, RECRUITING
- Improve thinking with brain stimulation, NCT05968703, RECRUITING
- Brain stimulation improves motor control, NCT04799470, RECRUITING
- Reduce hallucinations without worsening movement, NCT04373317, PHASE4, RECRUITING
- Early Parkinsons detection from gut, NCT05347407, RECRUITING
- Reduce medication wearing off fluctuations, NCT06928519, RECRUITING
- Test drug safety in Parkinson, NCT06466525, PHASE1, RECRUITING
- Improve sleep quality through exercise, NCT05644327, RECRUITING
- Improve insomnia with pallidal stimulation, NCT04116996, RECRUITING
- Detect early brain chemical changes, NCT04735172, RECRUITING