Clinical Trials for Parkinson's Depression and Anxiety
Depression and anxiety are among the most common non-motor symptoms of Parkinson's, and they are not simply a reaction to the diagnosis. The same brain changes that affect movement also affect mood, which is why these symptoms are an active area of research.
Trials in this area test medications, talk therapy and behavioral programs, exercise, and brain-stimulation approaches aimed at improving mood, along with studies that track how depression and anxiety change over time.
Below are the recruiting trials we track that focus on depression and anxiety. Sign up to be emailed when a new one opens.
71 Recruiting Depression & Anxiety Trials
- Map movement mood and sleep, NCT06536348, RECRUITING
- Improve movement with brain stimulation, NCT07524400, RECRUITING
- Targeted brain stimulation reduces depression, NCT06467695, RECRUITING
- Distinguish Parkinson from related disorders, NCT07509125, RECRUITING
- Treat Parkinson depression with probiotics, NCT05568498, PHASE2, RECRUITING
- Reduce apathy through personalized music, NCT05505019, RECRUITING
- Reduce overactive dopamine related behaviors, NCT07151378, PHASE3, RECRUITING
- Reduce freezing of gait episodes, NCT07316296, PHASE3, RECRUITING
- Reduce anxiety symptoms with mirtazapine, NCT06530290, PHASE2, RECRUITING
- Improve selfmanagement for nonmotor symptoms, NCT07038486, RECRUITING
- Improve social engagement and mood, NCT06385184, RECRUITING
- Preserve brain signals during surgery, NCT06543563, RECRUITING
- Reduce Parkinson fatigue through exercise, NCT06324422, RECRUITING
- Clear harmful brain protein clumps, NCT07157345, PHASE1, RECRUITING
- Reduce falls with treadmill training, NCT07058285, RECRUITING
- Brain stimulation helps thinking problems, NCT06399731, RECRUITING
- Improve walking through Amazonian dance, NCT06967493, RECRUITING
- Reduce pain and autonomic symptoms, NCT05748028, RECRUITING
- Improve patient mood with compassion, NCT07097298, RECRUITING
- Surgical brain stimulation reduces impulsivity, NCT06498349, RECRUITING
- Reduce depressive symptoms using ketamine, NCT06231563, PHASE2, RECRUITING
- Identify brain changes before symptoms, NCT07265596, PHASE2, RECRUITING
- Adaptive stimulation improves motor control, NCT07216976, RECRUITING
- Brain stimulation improves eye alignment, NCT05400499, RECRUITING
- Describe symptoms and blood tests, NCT03523052, RECRUITING
- Reduce freezing through brain stimulation, NCT06505460, RECRUITING
- Detect early cognitive decline Parkinsons, NCT05025254, RECRUITING
- Reduce memory impairment using levetiracetam, NCT04643327, PHASE2, RECRUITING
- Complementary medicine to reduce stiffness, NCT07207096, RECRUITING
- Confirm tremor control under anesthesia, NCT05550714, RECRUITING
- Reduce anxiety and improve functioning, NCT07310147, RECRUITING
- Prevent mania after brain stimulation, NCT05444907, RECRUITING
- Map dopamine signals for mood, NCT07402928, RECRUITING
- Improve walking speed through exercise, NCT07057219, RECRUITING
- Assess experimental pain in Parkinsons, NCT05981261, RECRUITING
- Improve walking speed with exercise, NCT06088355, RECRUITING
- Reduce motor symptoms using synbiotic, NCT05576818, PHASE3, RECRUITING
- Reduce depressive symptoms in Parkinsons, NCT06455293, PHASE2, RECRUITING
- Improve mood through caudate stimulation, NCT07409207, RECRUITING
- Identify serotonin abnormalities causing pain, NCT06008704, RECRUITING
- Improve cognition through supervised exercise, NCT05720468, RECRUITING
- Improve upper limb motor learning, NCT07028515, RECRUITING
- Acupuncture improves constipation and movement, NCT06304285, RECRUITING
- Determine if mutation affects thinking, NCT06329739, RECRUITING
- Rehabilitation measures meaningful daily improvements, NCT06487364, RECRUITING
- Measure cognitive decline in Parkinsons, NCT04997642, RECRUITING
- Increase walking speed and endurance, NCT06707402, RECRUITING
- How brain stimulation affects thinking, NCT06329726, RECRUITING
- Reduce complications through staff training, NCT06908460, RECRUITING
- Treat Parkinsons depression with ketamine, NCT06402955, PHASE2, RECRUITING