Clinical Trials for Parkinson's Depression and Anxiety
Depression and anxiety are among the most common non-motor symptoms of Parkinson's, and they are not just a reaction to the diagnosis. The same brain changes that affect movement also affect mood, which is why these symptoms are an active area of research.
Trials in this area test medications, talk therapy and behavioral programs, exercise, and brain-stimulation approaches aimed at improving mood, along with studies that track how depression and anxiety change over time.
Below are the recruiting trials we track that focus on depression and anxiety. Sign up to be emailed when a new one opens.
76 Recruiting Depression & Anxiety Trials
- Studying medication for Parkinsons depression, NCT07610369, PHASE2, RECRUITING
- Testing new Parkinson treatment approach, NCT07488351, RECRUITING
- Assess confidence in thinking skills, NCT07488377, RECRUITING
- Link imagining movements to frailty, NCT07488364, RECRUITING
- Predict impulse control from scans, NCT07213219, RECRUITING
- Improve eye alignment and refocusing, NCT06857851, RECRUITING
- Comparing Tai Chi Qigong balance, NCT07662837, RECRUITING
- Map movement mood and sleep, NCT06536348, RECRUITING
- Does aerobic training improve walking, NCT07478146, RECRUITING
- Improve movement with brain stimulation, NCT07524400, RECRUITING
- Studying guided stimulation for depression, NCT06467695, RECRUITING
- Distinguish Parkinson from related disorders, NCT07509125, RECRUITING
- Treat Parkinson depression with probiotics, NCT05568498, PHASE2, RECRUITING
- Reduce apathy through personalized music, NCT05505019, RECRUITING
- Reduce overactive dopamine related behaviors, NCT07151378, PHASE3, RECRUITING
- Reduce freezing of gait episodes, NCT07316296, PHASE3, RECRUITING
- Reduce anxiety symptoms with mirtazapine, NCT06530290, PHASE2, RECRUITING
- Improve selfmanagement for nonmotor symptoms, NCT07038486, RECRUITING
- Improve social engagement and mood, NCT06385184, RECRUITING
- Preserve brain signals during surgery, NCT06543563, RECRUITING
- Reduce Parkinson fatigue through exercise, NCT06324422, RECRUITING
- Clear harmful brain protein clumps, NCT07157345, PHASE1, RECRUITING
- Reduce falls with treadmill training, NCT07058285, RECRUITING
- Improve walking through Amazonian dance, NCT06967493, RECRUITING
- Reduce pain and autonomic symptoms, NCT05748028, RECRUITING
- Improve patient mood with compassion, NCT07097298, RECRUITING
- Surgical brain stimulation reduces impulsivity, NCT06498349, RECRUITING
- Reduce depressive symptoms using ketamine, NCT06231563, PHASE2, RECRUITING
- Identify brain changes before symptoms, NCT07265596, PHASE2, RECRUITING
- Brain stimulation improves eye alignment, NCT05400499, RECRUITING
- Describe symptoms and blood tests, NCT03523052, RECRUITING
- Reduce freezing through brain stimulation, NCT06505460, RECRUITING
- Can brain monitoring improve walking, NCT06690931, RECRUITING
- Detect early cognitive decline Parkinsons, NCT05025254, RECRUITING
- Reduce memory impairment using levetiracetam, NCT04643327, PHASE2, RECRUITING
- Complementary medicine to reduce stiffness, NCT07207096, RECRUITING
- Confirm tremor control under anesthesia, NCT05550714, RECRUITING
- Reduce anxiety and improve functioning, NCT07310147, RECRUITING
- Prevent mania after brain stimulation, NCT05444907, RECRUITING
- Map dopamine signals for mood, NCT07402928, RECRUITING
- Improve walking speed through exercise, NCT07057219, RECRUITING
- Assess experimental pain in Parkinsons, NCT05981261, RECRUITING
- Improve walking speed with exercise, NCT06088355, RECRUITING
- Reduce motor symptoms using synbiotic, NCT05576818, PHASE3, RECRUITING
- Reduce depressive symptoms in Parkinsons, NCT06455293, PHASE2, RECRUITING
- Improve mood through caudate stimulation, NCT07409207, RECRUITING
- Identify serotonin abnormalities causing pain, NCT06008704, RECRUITING
- Improve upper limb motor learning, NCT07028515, RECRUITING
- Can gut acupuncture ease movement, NCT06304285, RECRUITING
- Determine if mutation affects thinking, NCT06329739, RECRUITING